| Half-life | 24 hours |
| Clearance Route | mixed |
| Active Metabolites | yes |
| Notes | Once daily combination; strong BP lowering effect. |
Severity: Moderate
Adverse Effects:
Hyperkalemia, dizziness, renal impairment, hyponatremia
Contraindications:
Pregnancy, severe renal impairment
Precautions:
Monitor serum creatinine and electrolytes