Ropinirole
Brand: Requip (US/EU) / Ropin (IN) / Ropinex (BD)
Antiparkinson
Dopamine agonist (D2)
Pharmacokinetics
| Half-life | 6 hours |
| Tmax | 1.5 h |
| Bioavailability | 50 % (approx) |
| Protein Binding | 40 % |
| Volume of Distribution | 6 L/kg (approx) |
| Clearance Route | hepatic |
| Active Metabolites | yes |
| Notes | Also used first-line for restless legs syndrome. |
⚠️ Safety & Warnings
Severity: Moderate
Adverse Effects:
Nausea, dizziness, hypotension, impulse control disorders
Contraindications:
Known hypersensitivity
Precautions:
Monitor for compulsive behaviors and hallucinations, especially elderly