Letrozole
Brand: Femara
Endocrine
Aromatase Inhibitor
Chemistry
| PubChem |
CID: 3902 |
Structure
Pharmacokinetics
| Half-life | 2 days |
| Clearance Route | hepatic |
| Active Metabolites | uncertain |
| Notes | Letrozole t1/2 ≈ 45–48 hours |
⚠️ Safety & Warnings
Severity: Moderate
Adverse Effects:
Hot flashes, headache, arthralgia, fatigue
Contraindications:
Pregnancy, breastfeeding
Precautions:
Use caution in hepatic impairment