Celecoxib

Brand: Celebrex (global) / Oncoxel, Celcox (IN/BD common brands)

NSAID Selective COX-2 inhibitor

Chemistry

Molecular Formula	C17H14F3N3O2S
PubChem	CID: 2662 Open in PubChem

Structure

Half-life	11 hours
Clearance Route	hepatic
Active Metabolites	none
Notes	Metabolized via CYP2C9; avoid with strong CYP2C9 inhibitors. Increased risk of CV events with long-term use.

Severity: Moderate

Adverse Effects:
Dyspepsia, abdominal pain, edema, hypertension, rare hepatic injury, thrombotic risk

Contraindications:
Sulfonamide allergy, severe hepatic impairment, post-CABG pain

Precautions:
Monitor BP; use with caution in renal impairment and cardiovascular disease