Cefepime

Brand: Maxipime (US/EU) / Cefepime (IN/BD)

Antibiotic Cephalosporin 4th generation

Chemistry

Molecular Formula	C19H24N6O5S2
PubChem	CID: 5479532 Open in PubChem

Structure

Half-life	2 hours
Tmax	0.5 h
Bioavailability	100 % (approx)
Protein Binding	20 %
Volume of Distribution	0.2 L/kg (approx)
Clearance Route	renal
Active Metabolites	no
Notes	Typical dosing 1–2 g IV q8–12h depending on severity.

Severity: Severe

Adverse Effects:
Neurotoxicity (encephalopathy, seizures) especially in renal impairment; diarrhea

Contraindications:
Immediate beta-lactam anaphylaxis

Precautions:
Dose adjust strictly in renal impairment; monitor mental status