Exemestane
Brand: Aromasin (global)
Endocrine
Aromatase inhibitor (steroidal)
Pharmacokinetics
| Half-life | 27 hours |
| Clearance Route | hepatic |
| Active Metabolites | yes |
| Notes | Usual 25 mg/day; take after food to improve absorption. |
⚠️ Safety & Warnings
Severity: Moderate
Adverse Effects:
Hot flashes, arthralgia, fatigue, bone loss
Contraindications:
Premenopausal without ovarian suppression
Precautions:
Monitor bone health; consider bisphosphonate