Anticancer Class
Showing 5 drugs
starting with: D
Dabrafenib
Brand: Tafinlar (global)
Class: Anticancer
Subclass: BRAF inhibitor (V600E/K)
PK:
t½ 8 hours | Clearance: hepatic
Max Dose: 300 day
Max Dose: 300 day
moderate
AE: Fever, hyperglycemia, skin reactions, uveitis
AE: Fever, hyperglycemia, skin reactions, uveitis
Dasatinib
Brand: Sprycel (US/EU) / Dasatinib (IN/BD)
Class: Anticancer
Subclass: BCR-ABL Tyrosine Kinase Inhibitor
PK:
t½ 4 hours | Clearance: hepatic
Max Dose: 140 day
Max Dose: 140 day
severe
AE: Myelosuppression, pleural effusion, pulmonary hypertension
AE: Myelosuppression, pleural effusion, pulmonary hypertension
Daunorubicin
Brand: Cerubidine (global) / Daunoblastin (IN/BD)
Class: Anticancer
Subclass: Anthracycline (topoisomerase II inhibitor)
PK:
t½ 19 hours | Clearance: hepatic
Max Dose: not added
Max Dose: not added
life-threatening
AE: Myelosuppression, cardiomyopathy, mucositis, red/orange urine
AE: Myelosuppression, cardiomyopathy, mucositis, red/orange urine
Docetaxel
Brand: Taxotere (global) / Daxotel (IN/BD)
Class: Anticancer
Subclass: Taxane (microtubule stabilizer)
PK:
t½ 11 hours | Clearance: hepatic
Max Dose: not added
Max Dose: not added
severe
AE: Neutropenia, peripheral edema/fluid retention, mucositis, nail changes
AE: Neutropenia, peripheral edema/fluid retention, mucositis, nail changes
Durvalumab
Brand: Imfinzi (global) / Durvalumab (IN/BD)
Class: Anticancer
Subclass: PD-L1 Immune Checkpoint Inhibitor
PK:
t½ 432 hours | Clearance: hepatic
Max Dose: 1500 day
Max Dose: 1500 day
life-threatening
AE: Immune pneumonitis, hepatitis, colitis, endocrinopathy
AE: Immune pneumonitis, hepatitis, colitis, endocrinopathy