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Anticancer Class

Clear
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Showing 4 drugs starting with: E

Encorafenib

Brand: Braftovi (global)
Class: Anticancer
Subclass: BRAF inhibitor (V600E/K)
PK: t½ 6 hours | Clearance: hepatic
Max Dose: 450 day
moderate
AE: QT prolongation, ocular toxicity, hepatotoxicity, fatigue

Entrectinib

Brand: Rozlytrek (global)
Class: Anticancer
Subclass: NTRK / ROS1 inhibitor
PK: t½ 20 hours | Clearance: hepatic
Max Dose: 600 day
moderate
AE: Edema, dizziness, cognitive changes, weight gain, hepatotoxicity, CHF risk

Epirubicin

Brand: Ellence (global)
Class: Anticancer
Subclass: Anthracycline (topoisomerase II inhibitor)
PK: t½ 30 hours | Clearance: hepatic
Max Dose: not added
life-threatening
AE: Myelosuppression, cardiotoxicity, mucositis, alopecia

Erlotinib

Brand: Tarceva (US/EU) / Erlotinib (IN/BD)
Class: Anticancer
Subclass: EGFR Tyrosine Kinase Inhibitor
PK: t½ 36 hours | Clearance: hepatic
Max Dose: 150 day
severe
AE: Rash, diarrhoea, hepatotoxicity, interstitial lung disease (rare)