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Anticancer Class

Clear
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Showing 3 drugs starting with: I

Idarubicin

Brand: Idamycin (global)
Class: Anticancer
Subclass: Anthracycline (topoisomerase II inhibitor)
PK: t½ 22 hours | Clearance: hepatic
Max Dose: not added
life-threatening
AE: Cardiotoxicity, myelosuppression, nausea/vomiting, mucositis

Imatinib

Brand: Gleevec (US/EU) / Imatinib (IN/BD)
Class: Anticancer
Subclass: BCR-ABL Tyrosine Kinase Inhibitor
PK: t½ 18 hours | Clearance: hepatic
Max Dose: 800 day
moderate
AE: Fluid retention, edema, N/V, rash, cytopenias

Ipilimumab

Brand: Yervoy (global) / Ipilimumab (IN/BD)
Class: Anticancer
Subclass: CTLA-4 Immune Checkpoint Inhibitor
PK: t½ 360 hours | Clearance: other
Max Dose: 3 day
life-threatening
AE: Severe immune-mediated colitis, hepatitis, dermatitis, endocrine failure