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Anticancer Class

Clear
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Showing 3 drugs starting with: N

Neratinib

Brand: Nerlynx (global)
Class: Anticancer
Subclass: HER2 irreversible TKI
PK: t½ 17 hours | Clearance: hepatic
Max Dose: 240 day
severe
AE: Severe diarrhoea, hepatotoxicity, nausea, stomatitis

Nilotinib

Brand: Tasigna (US/EU) / Nilotinib (IN/BD)
Class: Anticancer
Subclass: BCR-ABL Tyrosine Kinase Inhibitor
PK: t½ 17 hours | Clearance: hepatic
Max Dose: 800 day
life-threatening
AE: QT prolongation, sudden death risk, hyperglycemia, hepatic toxicity

Niraparib

Brand: Zejula (global) / Niraparib (IN/BD)
Class: Anticancer
Subclass: PARP inhibitor
PK: t½ 36 hours | Clearance: hepatic
Max Dose: 300 day
moderate
AE: Thrombocytopenia, hypertension, nausea, fatigue