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Anticancer Class

Clear
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Showing 5 drugs starting with: T

Talazoparib

Brand: Talzenna (global) / Talazoparib (IN/BD)
Class: Anticancer
Subclass: PARP inhibitor
PK: t½ 90 hours | Clearance: hepatic
Max Dose: 1 day
moderate
AE: Anemia, neutropenia, thrombocytopenia, fatigue

Thalidomide

Brand: Thalomid (global)
Class: Anticancer
Subclass: Immunomodulatory agent (IMiD)
PK: t½ 6 hours | Clearance: hepatic
Max Dose: not added
life-threatening
AE: Sedation, constipation, peripheral neuropathy, thrombosis risk

Trametinib

Brand: Mekinist (global)
Class: Anticancer
Subclass: MEK inhibitor
PK: t½ 4 days | Clearance: hepatic
Max Dose: 2 day
severe
AE: Cardiomyopathy, retinopathy, diarrhea, hypertension, ILD

Trastuzumab

Brand: Herceptin (global) / Trastuzumab (IN/BD)
Class: Anticancer
Subclass: HER2 monoclonal antibody
PK: t½ 684 hours | Clearance: hepatic
Max Dose: 6 day
severe
AE: Cardiomyopathy, infusion reactions, pulmonary toxicity

Tucatinib

Brand: Tukysa (global)
Class: Anticancer
Subclass: HER2 selective TKI
PK: t½ 13 hours | Clearance: hepatic
Max Dose: 600 day
moderate
AE: Hepatotoxicity, diarrhoea, stomatitis, fatigue