Warfarin
Brand: Coumadin / Marevan / Warfilone
Class: Anticoagulant
Subclass: Vitamin K epoxide reductase inhibitor
PK:
t½ 36 hours | Clearance: hepatic
Max Dose: 10 day
severe
AE: Bleeding (GI, intracranial), skin necrosis (rare, protein C deficiency), purple toe syndrome, teratogenicity (fetal warfarin syndrome)