Immunomodulator Class
Showing 2 drugs
starting with: G
Golimumab
Brand: Simponi / Golimumax
Class: Immunomodulator
Subclass: TNF-alpha monoclonal antibody (IgG1κ)
PK:
t½ 14 days | Clearance: reticuloendothelial
Max Dose: not added
Max Dose: not added
severe
AE: Serious infections (TB, fungal), injection reactions, hepatotoxicity, demyelinating disease, CHF exacerbation
AE: Serious infections (TB, fungal), injection reactions, hepatotoxicity, demyelinating disease, CHF exacerbation
Guselkumab
Brand: Tremfya
Class: Immunomodulator
Subclass: IL-23 (p19) monoclonal antibody
PK:
t½ 16 days | Clearance: reticuloendothelial
Max Dose: not added
Max Dose: not added
moderate
AE: URTIs, headache, injection site reactions, arthralgia, diarrhea
AE: URTIs, headache, injection site reactions, arthralgia, diarrhea