Paracetamol + Tramadol
Brand: Ultracet / Tramapar / Tramacet
Subclass: Opioid + Non-opioid analgesic (FDC)
PK:
t½ 6 hours | Clearance: mixed
Max Dose: 8 day
moderate
AE: Drowsiness, dizziness, nausea, constipation; hepatotoxicity at high doses; serotonin syndrome risk; respiratory depression at high doses