All Drugs
Showing 8 drugs
starting with: B
Bedaquiline
Brand: Sirturo (global)
Class: Antibiotic
Subclass: Anti-TB (ATP synthase inhibitor)
PK:
t½ 164 days | Clearance: hepatic
Max Dose: 400 day
Max Dose: 400 day
life-threatening
AE: QT prolongation, hepatotoxicity, nausea, arthralgia
AE: QT prolongation, hepatotoxicity, nausea, arthralgia
Bevacizumab
Brand: Avastin (global) / Bevacizumab (IN/BD)
Class: Anticancer
Subclass: VEGF monoclonal antibody
PK:
t½ 480 hours | Clearance: hepatic
Max Dose: 15 day
Max Dose: 15 day
life-threatening
AE: Hypertension, proteinuria, arterial thromboembolism, GI perforation
AE: Hypertension, proteinuria, arterial thromboembolism, GI perforation
Binimetinib
Brand: Mektovi (global)
Class: Anticancer
Subclass: MEK inhibitor
PK:
t½ 9 hours | Clearance: hepatic
Max Dose: 90 day
Max Dose: 90 day
severe
AE: Retinal pigment epithelial detachment, CPK elevations, hepatotoxicity, diarrhea
AE: Retinal pigment epithelial detachment, CPK elevations, hepatotoxicity, diarrhea
Bisoprolol
Brand: Zebeta (US/EU) / Bisocor (IN) / Concor (IN/BD)
Class: Antihypertensive
Subclass: Beta-1 selective blocker
PK:
t½ 10 hours | Clearance: mixed
Max Dose: 10 day
Max Dose: 10 day
moderate
AE: Bradycardia, hypotension, dizziness, fatigue, sleep disturbance
AE: Bradycardia, hypotension, dizziness, fatigue, sleep disturbance
Bivalirudin
Brand: Angiomax (US/EU) / Bivasave (IN) / Bivacard (IN) / Bivaplex (BD)
Class: Anticoagulant
Subclass: Direct thrombin inhibitor (parenteral, procedural)
PK:
t½ 0.5 hours | Clearance: mixed
Max Dose: not added
Max Dose: not added
moderate
AE: Bleeding, hypotension, procedural hematoma
AE: Bleeding, hypotension, procedural hematoma
Brigatinib
Brand: Alunbrig (global)
Class: Anticancer
Subclass: ALK inhibitor (2nd gen)
PK:
t½ 26 hours | Clearance: hepatic
Max Dose: 180 day
Max Dose: 180 day
severe
AE: Pneumonitis (early onset), hypertension, visual disturbances, hyperglycemia, myalgia
AE: Pneumonitis (early onset), hypertension, visual disturbances, hyperglycemia, myalgia
Budesonide
Brand: Entocort EC (US/EU) / Budenofalk (EU) / Budecort (IN) / Budesonide (BD)
Class: Corticosteroid
Subclass: High first-pass glucocorticoid
PK:
t½ 3 hours | Clearance: hepatic
Max Dose: 9 day
Max Dose: 9 day
moderate
AE: Adrenal suppression (less than prednisolone), edema, mood changes
AE: Adrenal suppression (less than prednisolone), edema, mood changes
Bupropion
Brand: Wellbutrin (US/EU) / Bupep (IN) / Buproton (BD)
Class: Antidepressant
Subclass: NDRI (Norepinephrine-Dopamine Reuptake Inhibitor)
PK:
t½ 21 hours | Clearance: hepatic
Max Dose: 450 day
Max Dose: 450 day
severe
AE: Insomnia, agitation, tremor, dry mouth, seizures (dose dependent)
AE: Insomnia, agitation, tremor, dry mouth, seizures (dose dependent)