Categories

All Analgesic Analgesic Combination Antianginal Antibiotic Anticancer Anticoagulant Anticonvulsant Antidepressant Antidiabetic Antidiarrheal Antihypertensive Antimalarial Antiparasitic Antiparkinson Antiplatelet Antipsychotic Anxiolytic Bronchodilator Cardiovascular Corticosteroid Diuretic Emergency Endocrine Gastrointestinal Immunomodulator Immunosuppressant Minerals Neurological NSAID Oncology – Targeted therapy Psychiatric Sedative/Hypnotic Sympathomimetic Vitamins

All Drugs

Clear
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Showing 21 drugs starting with: D

Dabigatran

Brand: Pradaxa (US/EU) / Dabistar (IN) / Drabi (IN/BD)
Class: Anticoagulant
Subclass: NOAC / DOAC (Thrombin IIa inhibitor)
PK: t½ 12 hours | Clearance: renal
Max Dose: 300 day
moderate
AE: Bleeding (GI > cerebral), dyspepsia, gastritis-like symptoms due to acidic core, rare hypersensitivity

Dabrafenib

Brand: Tafinlar (global)
Class: Anticancer
Subclass: BRAF inhibitor (V600E/K)
PK: t½ 8 hours | Clearance: hepatic
Max Dose: 300 day
moderate
AE: Fever, hyperglycemia, skin reactions, uveitis

Dapagliflozin

Brand: Farxiga (US/EU) / Forxiga (EU) / Dapa (IN/BD)
Class: Antidiabetic
Subclass: SGLT2 inhibitor
PK: t½ 12 hours | Clearance: mixed
Max Dose: 10 day
moderate
AE: Genital mycotic infections, polyuria, volume depletion, rare euglycemic DKA

Dasatinib

Brand: Sprycel (US/EU) / Dasatinib (IN/BD)
Class: Anticancer
Subclass: BCR-ABL Tyrosine Kinase Inhibitor
PK: t½ 4 hours | Clearance: hepatic
Max Dose: 140 day
severe
AE: Myelosuppression, pleural effusion, pulmonary hypertension

Daunorubicin

Brand: Cerubidine (global) / Daunoblastin (IN/BD)
Class: Anticancer
Subclass: Anthracycline (topoisomerase II inhibitor)
PK: t½ 19 hours | Clearance: hepatic
Max Dose: not added
life-threatening
AE: Myelosuppression, cardiomyopathy, mucositis, red/orange urine

Delamanid

Brand: Deltyba (global)
Class: Antibiotic
Subclass: Anti-TB (nitro-dihydro-imidazooxazole)
PK: t½ 38 hours | Clearance: hepatic
Max Dose: 200 day
severe
AE: QT prolongation, GI upset, hypokalemia

Dexamethasone

Brand: Dexona
Class: Corticosteroid
Subclass: Long-acting Glucocorticoid
PK: t½ 48 hours | Clearance: hepatic
Max Dose: 16 day
moderate
AE: Hyperglycemia, insomnia, muscle wasting

Diazepam

Brand: Valium (US/EU) / Calmpose (IN) / Dzpam (BD)
Class: Anxiolytic
Subclass: Benzodiazepine anxiolytic (GABA-A positive allosteric modulator)
PK: t½ 48 hours | Clearance: hepatic
Max Dose: 40 day
severe
AE: Sedation, confusion, ataxia, respiratory depression, dependence

Diclofenac

Brand: Voveran
Class: NSAID
Subclass: COX inhibitor / Acetic acid derivative
PK: t½ 2 hours | Clearance: hepatic
Max Dose: 150 day
severe
AE: Gastritis, dyspepsia, edema, elevated liver enzymes, renal function decline RARE: GI bleeding, CV risk (MI/stroke) higher than ibuprofen

Diethylcarbamazine

Brand: Hetrazan / DEC
Class: Antiparasitic
Subclass: Microfilaricidal agent
PK: t½ 10 hours | Clearance: renal
Max Dose: not added
moderate
AE: Fever, headache, dizziness, nausea; allergic reactions due to microfilarial death (Mazzotti-type). Rare: proteinuria, leukocytosis.

Diloxanide Furoate

Brand: Furoxone / Diloxanide
Class: Antiparasitic
Subclass: Luminal amoebicide
PK: t½ 3 hours | Clearance: hepatic
Max Dose: not added
mild
AE: Flatulence, pruritus, nausea

Diltiazem

Brand: Cardizem (US/EU) / Angizem (IN) / Dilzem (BD)
Class: Antihypertensive
Subclass: Calcium channel blocker (Benzothiazepine)
PK: t½ 4 hours | Clearance: hepatic
Max Dose: 360 day
moderate
AE: Edema, bradycardia, headache, flushing, hypotension

Dipyridamole

Brand: Persantine (US/EU) / Pdyl (IN) / Aggrenox-combo (BD)
Class: Antiplatelet
Subclass: PDE inhibitor (vasodilatory antiplatelet)
PK: t½ 10 hours | Clearance: hepatic
Max Dose: 400 day
mild
AE: Headache, flushing, hypotension, dizziness, GI upset

Divalproex Sodium

Brand: Depakote (US) / Divaa (IN) / Divalon (BD)
Class: Anticonvulsant
Subclass: GABA agonist / HDAC inhibitor
PK: t½ 11 hours | Clearance: hepatic
Max Dose: 60 day
severe
AE: Hepatotoxicity, pancreatitis, tremor, sedation, weight gain, hair loss

Docetaxel

Brand: Taxotere (global) / Daxotel (IN/BD)
Class: Anticancer
Subclass: Taxane (microtubule stabilizer)
PK: t½ 11 hours | Clearance: hepatic
Max Dose: not added
severe
AE: Neutropenia, peripheral edema/fluid retention, mucositis, nail changes

Donepezil

Brand: Aricept (US/EU) / Donepezil (IN/BD)
Class: Neurological
Subclass: Acetylcholinesterase inhibitor (centrally acting)
PK: t½ 70 hours | Clearance: hepatic
Max Dose: 23 day
moderate
AE: Nausea, vomiting, diarrhea, anorexia, weight loss, insomnia, muscle cramps, dizziness, bradycardia, syncope

Dopamine

Brand: Dopamine (global)
Class: Emergency
Subclass: Catecholamine inotrope/vasopressor
PK: t½ 0.0333 hours | Clearance: hepatic
Max Dose: not added
severe
AE: Tachyarrhythmias, myocardial ischemia; extravasation injury

Doxycycline

Brand: Vibramycin (US/EU) / Doxy-1 (IN) / Doxicap (BD)
Class: Antibiotic
Subclass: Tetracycline
PK: t½ 18 hours | Clearance: mixed
Max Dose: 200 day
moderate
AE: GI upset, photosensitivity, esophagitis if taken lying down

Dulaglutide

Brand: Trulicity
Class: Antidiabetic
Subclass: GLP-1 receptor agonist (once-weekly)
PK: t½ 5 days | Clearance: other
Max Dose: 4.5 week
moderate
AE: Nausea, vomiting, diarrhea, abdominal pain, decreased appetite

Duloxetine

Brand: Cymbalta (US/EU) / Duzela (IN) / Dulox (BD)
Class: Antidepressant
Subclass: SNRI (Serotonin-norepinephrine reuptake inhibitor)
PK: t½ 12 hours | Clearance: hepatic
Max Dose: 120 day
moderate
AE: Nausea, dry mouth, constipation, insomnia, sexual dysfunction, increased sweating, hepatotoxicity risk

Durvalumab

Brand: Imfinzi (global) / Durvalumab (IN/BD)
Class: Anticancer
Subclass: PD-L1 Immune Checkpoint Inhibitor
PK: t½ 432 hours | Clearance: hepatic
Max Dose: 1500 day
life-threatening
AE: Immune pneumonitis, hepatitis, colitis, endocrinopathy