All Drugs

Showing 10 drugs starting with: O

Ofloxacin

Brand: Tarivid (US/EU) / Oflin (IN) / Oflax (BD)
Class: Antibiotic
Subclass: Fluoroquinolone
PK: t½ 6 hours | Clearance: renal
Max Dose: 800 day
severe
AE: Tendinopathy, dysglycemia, CNS effects

Olanzapine

Brand: Zyprexa (US/EU) / Olzap (IN) / Olanzin (BD)
Class: Antipsychotic
Subclass: Atypical antipsychotic (D2/5-HT2A antagonist)
PK: t½ 30 hours | Clearance: hepatic
Max Dose: 20 day
severe
AE: Severe weight gain, increased appetite, hyperglycemia, dyslipidemia, sedation, orthostatic hypotension

Olaparib

Brand: Lynparza (global) / Olaparib (IN/BD)
Class: Anticancer
Subclass: PARP inhibitor
PK: t½ 12 hours | Clearance: hepatic
Max Dose: 600 day
moderate
AE: Anemia, neutropenia, nausea, fatigue

Olmesartan

Brand: Benicar (US/EU) / Olkem (IN) / Olsar (IN) / Olmesar (BD)
Class: Antihypertensive
Subclass: Angiotensin II receptor blocker (ARB)
PK: t½ 13 hours | Clearance: hepatic
Max Dose: 40 day
moderate
AE: Dizziness, hyperkalemia, hypotension; rare sprue-like enteropathy presenting as chronic diarrhea

Olmesartan + Hydrochlorothiazide

Brand: Benicar HCT
Class: Antihypertensive
Subclass: ARB + Thiazide diuretic
PK: t½ 13 hours | Clearance: mixed
Max Dose: not added
moderate
AE: Hypotension, dizziness, hyperuricemia, hyperkalemia

Opicapone

Brand: Ongentys (global)
Class: Neurological
Subclass: COMT inhibitor (peripheral, long-acting)
PK: t½ 1.5 hours | Clearance: hepatic
Max Dose: 50 day
moderate
AE: Dyskinesia, constipation, hypotension, insomnia, elevated LFTs (rare)

Ornidazole

Brand: Ornida / Dazolic / Ornidazole (IN/BD generic)
Class: Antiparasitic
Subclass: Nitroimidazole Antiprotozoal
PK: t½ 12 hours | Clearance: hepatic
Max Dose: not added
moderate
AE: Nausea, metallic taste, dizziness, fatigue; rarely seizures or neuropathy.

Osimertinib

Brand: Tagrisso (global)
Class: Anticancer
Subclass: EGFR TKI (3rd gen)
PK: t½ 48 hours | Clearance: hepatic
Max Dose: 80 day
severe
AE: QT prolongation, ILD/pneumonitis, diarrhea, rash

Oxaliplatin

Brand: Eloxatin (global)
Class: Anticancer
Subclass: Platinum compound (DNA crosslinker)
PK: t½ 14 hours | Clearance: renal
Max Dose: not added
moderate
AE: Peripheral neuropathy (cold induced), nausea/vomiting, diarrhea, myelosuppression

Oxcarbazepine

Brand: Trileptal (US/EU) / Oxetol (IN) / Oxep (BD)
Class: Anticonvulsant
Subclass: Sodium channel blocker
PK: t½ 9 hours | Clearance: hepatic
Max Dose: 2400 day
moderate
AE: Hyponatremia (even more common than carbamazepine), dizziness, somnolence, rash