All Drugs

Showing 13 drugs starting with: N

Naloxone

Brand: Narcan (US/EU) / Nalox (IN/BD)
Class: Emergency
Subclass: Opioid antagonist
PK: t½ 1 hours | Clearance: hepatic
Max Dose: not added
life-threatening
AE: Acute withdrawal in opioid-dependent patients, agitation, hypertension

Naproxen

Brand: Napa-Extend
Class: NSAID
Subclass: Propionic acid derivative
PK: t½ 14 hours | Clearance: renal
Max Dose: 1000 day
moderate
AE: GI irritation, edema

Nebivolol

Brand: Bystolic (US/EU) / Nebicard (IN) / Nebilet (BD)
Class: Antihypertensive
Subclass: Beta-1 selective blocker with vasodilatory action
PK: t½ 12 hours | Clearance: hepatic
Max Dose: 10 day
moderate
AE: Headache, dizziness, fatigue, bradycardia, paresthesia

Neratinib

Brand: Nerlynx (global)
Class: Anticancer
Subclass: HER2 irreversible TKI
PK: t½ 17 hours | Clearance: hepatic
Max Dose: 240 day
severe
AE: Severe diarrhoea, hepatotoxicity, nausea, stomatitis

Niclosamide

Brand: Niclocide / Niclosan
Class: Antiparasitic
Subclass: Anthelmintic (tapeworm)
PK: t½ 6 hours | Clearance: hepatic
Max Dose: 2000 day
mild
AE: Nausea, vomiting, abdominal discomfort; rare pruritus

Nifedipine

Brand: Adalat (US/EU) / Nicardia (IN) / Nifedip (BD)
Class: Antihypertensive
Subclass: Calcium channel blocker (Dihydropyridine)
PK: t½ 2 hours | Clearance: hepatic
Max Dose: 120 day
moderate
AE: Headache, flushing, dizziness, ankle edema, reflex tachycardia

Nilotinib

Brand: Tasigna (US/EU) / Nilotinib (IN/BD)
Class: Anticancer
Subclass: BCR-ABL Tyrosine Kinase Inhibitor
PK: t½ 17 hours | Clearance: hepatic
Max Dose: 800 day
life-threatening
AE: QT prolongation, sudden death risk, hyperglycemia, hepatic toxicity

Niraparib

Brand: Zejula (global) / Niraparib (IN/BD)
Class: Anticancer
Subclass: PARP inhibitor
PK: t½ 36 hours | Clearance: hepatic
Max Dose: 300 day
moderate
AE: Thrombocytopenia, hypertension, nausea, fatigue

Nitazoxanide

Brand: Alinia / Nizonide (IN/BD)
Class: Antiparasitic
Subclass: Antiprotozoal / Antihelminthic
PK: t½ 3 hours | Clearance: hepatic
Max Dose: not added
moderate
AE: Abdominal pain, nausea, headache, elevated LFTs

Nitrofurantoin

Brand: Macrobid/Macrodantin (US/EU) / Nitrofur (IN/BD)
Class: Antibiotic
Subclass: Nitrofuran (urinary antiseptic)
PK: t½ 0.5 hours | Clearance: renal
Max Dose: 400 day
moderate
AE: GI upset, headache; rare pulmonary/hepatic toxicity with long-term use

Nitroglycerin

Brand: Nitrostat (US/EU) / Angised (IN) / Nitroglycerin (BD)
Class: Antianginal
Subclass: Organic nitrate vasodilator
PK: t½ 0.3 hours | Clearance: hepatic
Max Dose: 15 day
moderate
AE: Headache, flushing, hypotension, reflex tachycardia, dizziness, syncope

Noradrenaline

Brand: Norepinephrine (US/EU) / Norad (IN/BD)
Class: Emergency
Subclass: Catecholamine vasopressor
PK: t½ 0.0417 hours | Clearance: hepatic
Max Dose: not added
life-threatening
AE: Tachyarrhythmias, ischemia, peripheral vasoconstriction/necrosis if extravasated

Nortriptyline

Brand: Pamelor (US/EU) / Nortrilop (IN) / Nortrip (BD)
Class: Antidepressant
Subclass: TCA (Tricyclic antidepressant)
PK: t½ 30 hours | Clearance: hepatic
Max Dose: 100 day
moderate
AE: Dry mouth, constipation, arrhythmia risk, dizziness, sedation