All Drugs
Showing 19 drugs
starting with: T
Talazoparib
Brand: Talzenna (global) / Talazoparib (IN/BD)
Class: Anticancer
Subclass: PARP inhibitor
PK:
t½ 90 hours | Clearance: hepatic
Max Dose: 1 day
Max Dose: 1 day
moderate
AE: Anemia, neutropenia, thrombocytopenia, fatigue
AE: Anemia, neutropenia, thrombocytopenia, fatigue
Tamoxifen
Brand: Nolvadex
Class: Endocrine
Subclass: SERM
PK:
t½ 6 days | Clearance: hepatic
Max Dose: not added
Max Dose: not added
Tapentadol
Brand: Nucynta / Palexia
Class: Analgesic
Subclass: Opioid analgesic (µ-opioid agonist + norepinephrine reuptake inhibitor)
PK:
t½ 4 hours | Clearance: hepatic
Max Dose: 700 day
Max Dose: 700 day
severe
AE: Nausea, vomiting, dizziness, somnolence, constipation, headache, respiratory depression
AE: Nausea, vomiting, dizziness, somnolence, constipation, headache, respiratory depression
Telmisartan
Brand: Micardis (US/EU) / Telma (IN) / Telsartan (IN) / Telsar (BD)
Class: Antihypertensive
Subclass: Angiotensin II receptor blocker (ARB)
PK:
t½ 24 hours | Clearance: hepatic
Max Dose: 80 day
Max Dose: 80 day
moderate
AE: Dizziness, hyperkalemia, mild GI upset; rare angioedema
AE: Dizziness, hyperkalemia, mild GI upset; rare angioedema
Telmisartan + Hydrochlorothiazide
Brand: Micardis HCT
Class: Antihypertensive
Subclass: ARB + Thiazide diuretic
PK:
t½ 24 hours | Clearance: mixed
Max Dose: not added
Max Dose: not added
moderate
AE: Hyperkalemia, dizziness, renal impairment, hyponatremia
AE: Hyperkalemia, dizziness, renal impairment, hyponatremia
Temazepam
Brand: Restoril (US) / Temsun (IN) / Restozam (BD)
Class: Sedative/Hypnotic
Subclass: Benzodiazepine hypnotic (GABA-A positive allosteric modulator)
PK:
t½ 10 hours | Clearance: hepatic
Max Dose: 30 day
Max Dose: 30 day
moderate
AE: Daytime drowsiness, impaired coordination, memory impairment, dependency
AE: Daytime drowsiness, impaired coordination, memory impairment, dependency
Teneligliptin
Brand: Tenepure/Tenepride (IN/BD)
Class: Antidiabetic
Subclass: DPP-4 inhibitor
PK:
t½ 24 hours | Clearance: hepatic
Max Dose: 40 day
Max Dose: 40 day
mild
AE: Nasopharyngitis, mild GI upset, rare hepatic enzyme elevation
AE: Nasopharyngitis, mild GI upset, rare hepatic enzyme elevation
Terbutaline
Brand: Bricanyl (global)
Class: Bronchodilator
Subclass: Short-acting β2 agonist (SABA)
PK:
t½ 4 hours | Clearance: hepatic
Max Dose: 15 day
Max Dose: 15 day
moderate
AE: Tachycardia, tremors, hypokalemia, hyperglycemia
AE: Tachycardia, tremors, hypokalemia, hyperglycemia
Thalidomide
Brand: Thalomid (global)
Class: Anticancer
Subclass: Immunomodulatory agent (IMiD)
PK:
t½ 6 hours | Clearance: hepatic
Max Dose: not added
Max Dose: not added
life-threatening
AE: Sedation, constipation, peripheral neuropathy, thrombosis risk
AE: Sedation, constipation, peripheral neuropathy, thrombosis risk
Ticagrelor
Brand: Brilinta (US/EU) / Ticawell (IN) / Ticaflo (IN) / Ticadro (BD)
Class: Antiplatelet
Subclass: P2Y12 inhibitor (reversible, not a prodrug)
PK:
t½ 7 hours | Clearance: hepatic
Max Dose: 180 day
Max Dose: 180 day
Tinidazole
Brand: Tindamax (US) / Fasigyn (Global)
Class: Antiparasitic
Subclass: Nitroimidazole Antiprotozoal
PK:
t½ 12.5 hours | Clearance: hepatic
Max Dose: not added
Max Dose: not added
moderate
AE: Metallic taste, nausea, fatigue, dizziness; rare peripheral neuropathy; dark urine.
AE: Metallic taste, nausea, fatigue, dizziness; rare peripheral neuropathy; dark urine.
Tirofiban
Brand: Aggrastat (US/EU) / Aggril (IN) / Tirof (BD)
Class: Antiplatelet
Subclass: GP IIb/IIIa inhibitor (IV, small-molecule)
PK:
t½ 2 hours | Clearance: renal
Max Dose: not added
Max Dose: not added
moderate
AE: Bleeding, thrombocytopenia, hypotension
AE: Bleeding, thrombocytopenia, hypotension
Tirzepatide
Brand: Mounjaro (US/EU) / Zepbound (US)
Class: Antidiabetic
Subclass: Dual GIP and GLP-1 receptor agonist
PK:
t½ 120 hours | Clearance: other
Max Dose: 15 week
Max Dose: 15 week
moderate
AE: Nausea, vomiting, diarrhea, decreased appetite, delayed gastric emptying
AE: Nausea, vomiting, diarrhea, decreased appetite, delayed gastric emptying
Tolcapone
Brand: Tasmar (US/EU) / Tolcap (IN) / Tolcom (BD)
Class: Antiparkinson
Subclass: COMT inhibitor
PK:
t½ 2 hours | Clearance: hepatic
Max Dose: 600 day
Max Dose: 600 day
severe
AE: Severe hepatotoxicity, diarrhea, dyskinesias, nausea
AE: Severe hepatotoxicity, diarrhea, dyskinesias, nausea
Topiramate
Brand: Topamax (US/EU) / Topamac (IN) / Topamax (BD)
Class: Anticonvulsant
Subclass: Sodium channel blocker / GABA enhancer / carbonic anhydrase inhibitor
PK:
t½ 21 hours | Clearance: renal
Max Dose: 400 day
Max Dose: 400 day
moderate
AE: Paresthesia, cognitive slowing, word-finding difficulty, weight loss, kidney stones, metabolic acidosis
AE: Paresthesia, cognitive slowing, word-finding difficulty, weight loss, kidney stones, metabolic acidosis
Tramadol
Brand: Ultram (US) / Tramazac (IN) / Tramafen (BD)
Class: Analgesic
Subclass: Opioid analgesic (atypical)
PK:
t½ 6 hours | Clearance: mixed
Max Dose: 400 day
Max Dose: 400 day
moderate
AE: Nausea, dizziness, somnolence, constipation, seizures, serotonin syndrome, respiratory depression
AE: Nausea, dizziness, somnolence, constipation, seizures, serotonin syndrome, respiratory depression
Trametinib
Brand: Mekinist (global)
Class: Anticancer
Subclass: MEK inhibitor
PK:
t½ 4 days | Clearance: hepatic
Max Dose: 2 day
Max Dose: 2 day
severe
AE: Cardiomyopathy, retinopathy, diarrhea, hypertension, ILD
AE: Cardiomyopathy, retinopathy, diarrhea, hypertension, ILD
Trastuzumab
Brand: Herceptin (global) / Trastuzumab (IN/BD)
Class: Anticancer
Subclass: HER2 monoclonal antibody
PK:
t½ 684 hours | Clearance: hepatic
Max Dose: 6 day
Max Dose: 6 day
severe
AE: Cardiomyopathy, infusion reactions, pulmonary toxicity
AE: Cardiomyopathy, infusion reactions, pulmonary toxicity
Tucatinib
Brand: Tukysa (global)
Class: Anticancer
Subclass: HER2 selective TKI
PK:
t½ 13 hours | Clearance: hepatic
Max Dose: 600 day
Max Dose: 600 day
moderate
AE: Hepatotoxicity, diarrhoea, stomatitis, fatigue
AE: Hepatotoxicity, diarrhoea, stomatitis, fatigue