Drugs by Class

Racecadotril

Brand: Hidrasec / Redotil / Racecadotril

Class: Gastrointestinal

Subclass: Antisecretory antidiarrheal (Enkephalinase inhibitor)

PK: t½ 3 hours | Clearance: hepatic
Max Dose: 300 day

mild
AE: Headache, nausea, abdominal discomfort, rash (rare)

Ramipril

Brand: Altace (US/EU) / Ramipres (IN) / Ramiace (BD)

Class: Antihypertensive

Subclass: ACE inhibitor (prodrug)

PK: t½ 13 hours | Clearance: mixed
Max Dose: 10 day

moderate
AE: Dry cough, hyperkalemia, dizziness, renal function changes, angioedema (rare but serious)

Ranolazine

Brand: Ranexa (US/EU) / Ranozex (IN) / Ranolaz (BD)

Class: Antianginal

Subclass: Late sodium-current inhibitor

PK: t½ 7 hours | Clearance: hepatic
Max Dose: 1000 day

moderate
AE: Dizziness, constipation, nausea, headache, QT interval prolongation

Rasagiline

Brand: Azilect (US/EU) / Rasagin (IN) / Rasact (BD)

Class: Antiparkinson

Subclass: MAO-B inhibitor

PK: t½ 7 hours | Clearance: hepatic
Max Dose: 1 day

moderate
AE: Headache, arthralgia, depression, nausea

Reserpine

Brand: Serpalan (US/EU) / Respin (IN) / Reserpine (BD)

Class: Antihypertensive

Subclass: Adrenergic neuron blocker

PK: t½ 100 hours | Clearance: hepatic
Max Dose: 0.5 day

severe
AE: Depression, nasal congestion, diarrhea, bradycardia, sedation, peptic ulcer exacerbation

Ribociclib

Brand: Kisqali

Class: Anticancer

Subclass: CDK4/6 inhibitor

PK: t½ 32 hours | Clearance: hepatic
Max Dose: 600 day

severe
AE: Neutropenia, hepatotoxicity, QT prolongation

Rifampicin

Brand: Rimactane (US/EU) / Rcin (IN/BD)

Class: Antibiotic

Subclass: Anti-TB (Rifamycin)

PK: t½ 3 hours | Clearance: hepatic
Max Dose: 600 day

severe
AE: Hepatotoxicity, orange urine/tears/sweat, flu-like syndrome

Risankizumab

Brand: Skyrizi

Class: Immunomodulator

Subclass: IL-23 (p19) monoclonal antibody

PK: t½ 28 days | Clearance: reticuloendothelial
Max Dose: not added

moderate
AE: URTI, headache, injection site reactions, fatigue

Risperidone

Brand: Risperdal (US/EU) / Sizodon (IN) / Risp (BD)

Class: Antipsychotic

Subclass: Atypical antipsychotic (D2/5-HT2A antagonist)

PK: t½ 20 hours | Clearance: hepatic
Max Dose: 6 day

moderate
AE: Hyperprolactinemia, weight gain, metabolic syndrome, extrapyramidal symptoms, sedation

Rivaroxaban

Brand: Xarelto (US/EU) / Rivaxa (IN) / Rivarox (IN) / Xavira (BD)

Class: Anticoagulant

Subclass: NOAC / DOAC (Xa inhibitor)

PK: t½ 9 hours | Clearance: mixed
Max Dose: 20 day

moderate
AE: Bleeding (GI > cerebral), dyspepsia, rare hepatic injury

Rivastigmine

Brand: Exelon (US/EU) / Rivamer (IN) / Rivastigmine (BD)

Class: Neurological

Subclass: Cholinesterase inhibitor (AChE + BuChE; pseudo-irreversible)

PK: t½ 1.5 hours | Clearance: renal
Max Dose: 12 day

moderate
AE: Nausea, vomiting, diarrhea, anorexia/weight loss, dizziness, bradycardia, syncope, tremor; patch: application-site reactions

Ropinirole

Brand: Requip (US/EU) / Ropin (IN) / Ropinex (BD)

Class: Antiparkinson

Subclass: Dopamine agonist (D2)

PK: t½ 6 hours | Clearance: hepatic
Max Dose: 24 day

moderate
AE: Nausea, dizziness, hypotension, impulse control disorders

Rosuvastatin

Brand: Crestor (US/EU) / Rosuvas (IN) / Rosumix (BD)

Class: Cardiovascular

Subclass: Statin (HMG-CoA reductase inhibitor)

PK: t½ 19 hours | Clearance: hepatic
Max Dose: 40 day

moderate
AE: Myalgia, ALT elevation, rare rhabdomyolysis

Rotigotine

Brand: Neupro (global)

Class: Neurological

Subclass: Dopamine agonist (non-ergot, transdermal patch)

PK: t½ 5.7 hours | Clearance: hepatic
Max Dose: 16 day

moderate
AE: Nausea, dizziness, somnolence, hallucinations, orthostatic hypotension, skin irritation at patch site

Roxithromycin

Brand: Roxid (IN) / Roxim (BD)

Class: Antibiotic

Subclass: Macrolide

PK: t½ 12 hours | Clearance: hepatic
Max Dose: 300 day

moderate
AE: GI upset, mild QT prolongation

Rucaparib

Brand: Rubraca (global) / Rucaparib (IN/BD)