All Drugs

Cabergoline

Brand: Cabaser

Class: Endocrine

Subclass: Dopamine agonist

PK: t½ 65 hours | Clearance: hepatic
Max Dose: 1 day

moderate
AE: Nausea, dizziness, hypotension

Calcium: Calcium carbonate

Class: Minerals

Subclass: Calcium supplement

PK: t½ not added | Clearance: not added
Max Dose: not added

Calcium: Calcium citrate

Class: Minerals

Subclass: Calcium supplement

PK: t½ not added | Clearance: not added
Max Dose: not added

Canagliflozin

Brand: Invokana (US/EU) / Cana (IN/BD)

Class: Antidiabetic

Subclass: SGLT2 inhibitor

PK: t½ 12 hours | Clearance: mixed
Max Dose: 300 day

moderate
AE: Genital mycotic infection, polyuria, volume depletion, euglycemic DKA (rare), ↑fracture/amputation signal

Candesartan

Brand: Atacand (US/EU) / Candesar (IN) / Candebloc (IN) / Candesar (BD)

Class: Antihypertensive

Subclass: Angiotensin II receptor blocker (ARB)

PK: t½ 9 hours | Clearance: hepatic
Max Dose: 32 day

moderate
AE: Dizziness, hyperkalemia, hypotension; rare renal function changes

Cangrelor

Brand: Kengreal (US/EU) / Cangrelor (IN) / Kengreal (BD)

Class: Antiplatelet

Subclass: P2Y12 inhibitor (IV, reversible, rapid onset)

PK: t½ 0.1 hours | Clearance: other
Max Dose: not added

moderate
AE: Bleeding, hypotension, dyspnea

Capecitabine

Brand: Xeloda (global)

Class: Anticancer

Subclass: Antimetabolite (oral prodrug of 5-FU)

PK: t½ 0.75 hours | Clearance: hepatic
Max Dose: not added

severe
AE: Diarrhea, hand-foot syndrome, mucositis, fatigue, cardiotoxicity (rare)

Capmatinib

Brand: Tabrecta (global)

Class: Anticancer

Subclass: MET inhibitor

PK: t½ 6.5 hours | Clearance: hepatic
Max Dose: 800 day

moderate
AE: Peripheral edema, nausea, fatigue, photosensitivity, ILD/pneumonitis

Captopril

Brand: Capoten (US/EU) / Captol (IN) / Captopril (BD)

Class: Antihypertensive

Subclass: ACE inhibitor (short-acting)

PK: t½ 2 hours | Clearance: renal
Max Dose: 150 day

moderate
AE: Dry cough, hyperkalemia, skin rash, dysgeusia (metallic taste), hypotension, angioedema

Carbamazepine

Brand: Tegretol (US/EU) / Zeptol (IN) / Carbolith (BD)

Class: Anticonvulsant

Subclass: Sodium channel blocker

PK: t½ 15 hours | Clearance: hepatic
Max Dose: 1200 day

severe
AE: Sedation, ataxia, dizziness, hyponatremia (SIADH), bone marrow suppression, rash

Carbidopa + Levodopa

Brand: Sinemet (US/EU) / Syndopa (IN) / Tidomet (BD)

Class: Antiparkinson

Subclass: Dopamine precursor + peripheral decarboxylase inhibitor

PK: t½ 1.5 hours | Clearance: hepatic
Max Dose: 1500 day

moderate
AE: Nausea, dizziness, dyskinesias, hallucinations, orthostatic hypotension

Carboplatin

Brand: Paraplatin (global)

Class: Anticancer

Subclass: Platinum compound (DNA crosslinker)

PK: t½ 5 hours | Clearance: renal
Max Dose: not added

moderate
AE: Myelosuppression (especially thrombocytopenia), nausea/vomiting, less nephrotoxicity than cisplatin

Carvedilol

Brand: Coreg (US/EU) / Carloc (IN) / Dilatrend (BD)

Class: Antihypertensive

Subclass: Alpha and beta blocker

PK: t½ 7 hours | Clearance: hepatic
Max Dose: 50 day

moderate
AE: Hypotension, bradycardia, dizziness, fatigue, orthostatic symptoms

Cefalexin

Brand: Keflex (US/EU) / Cefakind (IN) / Cefalexin (BD)

Class: Antibiotic

Subclass: Cephalosporin 1st generation

PK: t½ 1 hours | Clearance: renal
Max Dose: 4000 day

mild
AE: GI upset, rash, diarrhea

Cefepime

Brand: Maxipime (US/EU) / Cefepime (IN/BD)

Class: Antibiotic

Subclass: Cephalosporin 4th generation

PK: t½ 2 hours | Clearance: renal
Max Dose: 6000 day

severe
AE: Neurotoxicity (encephalopathy, seizures) especially in renal impairment; diarrhea

Cefixime

Brand: Suprax (US/EU) / Taxim-O (IN) / Cef-3 (BD)

Class: Antibiotic

Subclass: Cephalosporin 3rd generation (oral)

PK: t½ 3.5 hours | Clearance: renal
Max Dose: 400 day

moderate
AE: Diarrhea, dyspepsia, mild hepatic enzyme rise

Ceftaroline

Brand: Teflaro (US/EU)

Class: Antibiotic

Subclass: Cephalosporin 5th generation (MRSA active)

PK: t½ 2.6 hours | Clearance: renal
Max Dose: 1200 day

moderate
AE: GI upset, neutropenia, rash

Ceftriaxone

Brand: Rocephin (US/EU) / Ceftrion (IN/BD)

Class: Antibiotic

Subclass: Cephalosporin 3rd generation (parenteral)

PK: t½ 8 hours | Clearance: mixed
Max Dose: 4000 day

severe
AE: Biliary sludging, diarrhea, injection-site pain

Cefuroxime

Brand: Zinacef (IV) / Ceftin (US/EU oral) / Cefurox (IN/BD)

Class: Antibiotic

Subclass: Cephalosporin 2nd generation

PK: t½ 1.5 hours | Clearance: renal
Max Dose: 1500 day

moderate
AE: GI upset, diarrhea, rash

Celecoxib

Brand: Celebrex (global) / Oncoxel, Celcox (IN/BD common brands)

Class: NSAID

Subclass: Selective COX-2 inhibitor

PK: t½ 11 hours | Clearance: hepatic
Max Dose: 400 day

moderate
AE: Dyspepsia, abdominal pain, edema, hypertension, rare hepatic injury, thrombotic risk

Cemiplimab

Brand: Libtayo (global)

Class: Anticancer

Subclass: PD-1 monoclonal antibody

PK: t½ 19 days | Clearance: hepatic
Max Dose: not added

severe
AE: Immune mediated pneumonitis, colitis, hepatitis, endocrinopathies

Ceritinib

Brand: Zykadia (global)

Class: Anticancer

Subclass: ALK inhibitor (2nd generation)

PK: t½ 1.7 days | Clearance: hepatic
Max Dose: 450 day

moderate
AE: Severe GI toxicity (diarrhea, nausea), hepatotoxicity, QT prolongation, hyperglycemia

Certolizumab Pegol

Brand: Cimzia

Class: Immunomodulator

Subclass: PEGylated anti–TNF-α antibody fragment (Fab’)

PK: t½ 14 days | Clearance: reticuloendothelial
Max Dose: not added

severe
AE: Infections (TB, invasive fungal), injection reactions, hepatotoxicity, cytopenias, malignancy risk

Chloroquine

Brand: Nivaquine / generic chloroquine

Class: Antimalarial

Subclass: 4-aminoquinoline

PK: t½ 30 days | Clearance: hepatic
Max Dose: 2500 day

moderate
AE: Pruritus, GI upset, headache, visual disturbances, rare retinopathy, QT prolongation at high dose or IV use.

Chlorthalidone

Brand: Hygroton / Thalitone

Class: Diuretic

Subclass: Thiazide-like diuretic

PK: t½ 50 hours | Clearance: renal
Max Dose: 25 day

moderate
AE: Hyponatremia, hypokalemia, hyperuricemia

Cilostazol

Brand: Pletal (US/EU) / Cilacar (IN) / Cilodoc (IN) / Cilosta (BD)

Class: Antiplatelet

Subclass: PDE-III inhibitor (antiplatelet + vasodilator)

PK: t½ 12 hours | Clearance: hepatic
Max Dose: 200 day

moderate
AE: Headache, palpitations, tachycardia, edema, diarrhea

Ciprofloxacin

Brand: Cipro (US/EU) / Cifran (IN) / Ciprogen (BD)

Class: Antibiotic

Subclass: Fluoroquinolone

PK: t½ 4 hours | Clearance: renal
Max Dose: 1500 day

severe
AE: Tendonitis, tendon rupture, CNS effects, QT prolongation, dysglycemia

Cisplatin

Brand: Platinol (global)

Class: Anticancer

Subclass: Platinum compound (DNA crosslinker)

PK: t½ 70 hours | Clearance: renal
Max Dose: not added

severe
AE: Nephrotoxicity, ototoxicity, peripheral neuropathy, severe nausea/vomiting

Citalopram

Brand: Celexa (US) / Stalopam (IN) / Citadep (BD)

Class: Antidepressant

Subclass: SSRI (Selective serotonin reuptake inhibitor)

PK: t½ 35 hours | Clearance: hepatic
Max Dose: 40 day

moderate
AE: QT prolongation, sexual dysfunction, nausea, insomnia

Citicoline

Brand: CDP-Choline / Citicoline (various)

Class: Neurological

Subclass: Neuroprotective / cholinergic precursor

PK: t½ 56 hours | Clearance: renal
Max Dose: 2000 day

mild
AE: Headache, insomnia, nausea, diarrhea; rarely hypotension

Clarithromycin

Brand: Biaxin (US/EU) / Claribid (IN) / Claric (BD)

Class: Antibiotic

Subclass: Macrolide

PK: t½ 5 hours | Clearance: hepatic
Max Dose: 1000 day

severe
AE: GI upset, taste disturbance, QT prolongation

Clofazimine

Brand: Lamprene (global) / Clofaz (IN/BD)

Class: Antibiotic

Subclass: Anti-TB (riminophenazine)

PK: t½ 70 days | Clearance: hepatic
Max Dose: 100 day

moderate
AE: Skin discoloration red→brown→black, GI pain, photosensitivity

Clomiphene

Brand: Clomid

Class: Endocrine

Subclass: SERM

PK: t½ 5 days | Clearance: hepatic
Max Dose: 150 day

moderate
AE: Ovarian enlargement, hot flashes, visual disturbances

Clomipramine

Brand: Anafranil (US/EU) / Clonil (IN) / Clomicalm (BD)

Class: Antidepressant

Subclass: TCA (Tricyclic antidepressant)

PK: t½ 32 hours | Clearance: hepatic
Max Dose: 250 day

severe
AE: Sexual dysfunction, weight gain, constipation, arrhythmias, seizure threshold lowering

Clonazepam

Brand: Klonopin (US/EU) / Lonazep (IN) / Clonapam (BD)

Class: Anxiolytic

Subclass: Benzodiazepine anxiolytic (GABA-A positive allosteric modulator)

PK: t½ 34 hours | Clearance: hepatic
Max Dose: 4 day

severe
AE: Sedation, confusion, impaired coordination, dependence, withdrawal seizures

Clonidine

Brand: Catapres (US/EU) / Arkamin (IN) / Clonid (BD)

Class: Antihypertensive

Subclass: Centrally acting α₂-adrenergic agonist

PK: t½ 12 hours | Clearance: renal
Max Dose: 0.9 day

moderate
AE: Sedation, dry mouth, bradycardia, rebound hypertension, constipation

Clopidogrel

Brand: Plavix (US/EU) / Clopitab (IN) / Clopivas (IN) / Clopid (BD)

Class: Antiplatelet

Subclass: P2Y12 inhibitor (thienopyridine, prodrug)

PK: t½ 8 hours | Clearance: hepatic
Max Dose: 600 day

moderate
AE: Bleeding (GI/intracranial), dyspepsia, rash; RARE: thrombotic thrombocytopenic purpura (TTP), neutropenia

Cloxacillin

Brand: Orbenin (EU) / Cloxacil (IN/BD)

Class: Antibiotic

Subclass: Anti-staphylococcal penicillin

PK: t½ 0.8 hours | Clearance: mixed
Max Dose: 4000 day

moderate
AE: GI upset, rash, cholestatic hepatitis (rare but well-known)

Cobimetinib

Brand: Cotellic (global)

Class: Anticancer

Subclass: MEK inhibitor

PK: t½ 44 hours | Clearance: hepatic
Max Dose: 60 day

severe
AE: Rhabdomyolysis, CPK elevation, serous retinopathy, diarrhea

Cotrimoxazole (TMP-SMX)

Brand: Bactrim (US/EU) / Septran (IN) / Cotrim (BD)

Class: Antibiotic

Subclass: Folate pathway inhibitor combo (TMP+SMX)

PK: t½ 10 hours | Clearance: mixed
Max Dose: 640 day

severe
AE: Rash (SJS/TEN rare), hyperkalemia, bone marrow suppression, photosensitivity

Crizotinib

Brand: Xalkori (global)

Class: Anticancer

Subclass: ALK / ROS1 inhibitor (1st gen)

PK: t½ 42 hours | Clearance: hepatic
Max Dose: 500 day

moderate
AE: Visual disturbances (common), QT prolongation, hepatotoxicity, GI upset, bradycardia

Cycloserine

Brand: Seromycin (global) / Cyslin (IN)

Class: Antibiotic

Subclass: Anti-TB (D-alanine analog)

PK: t½ 10 hours | Clearance: renal
Max Dose: 750 day

life-threatening
AE: Depression, psychosis, suicidal ideation, seizures

Cytarabine

Brand: DepoCyt (liposomal) / Cytarabine generic

Class: Anticancer

Subclass: Antimetabolite (pyrimidine analogue)

PK: t½ 1.5 hours | Clearance: hepatic
Max Dose: not added

severe
AE: Myelosuppression, cerebellar toxicity (high dose), conjunctivitis