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Showing 19 drugs starting with: M

Magnesium: Magnesium oxide

Class: Minerals
Subclass: Magnesium supplement
PK: t½ not added | Clearance: not added
Max Dose: not added

Magnesium: Magnesium sulfate

Class: Minerals
Subclass: Magnesium (parenteral)
PK: t½ not added | Clearance: not added
Max Dose: not added

Mebendazole

Brand: Vermox / Meben (generic)
Class: Antiparasitic
Subclass: Benzimidazole anthelmintic
PK: t½ 3 hours | Clearance: hepatic
Max Dose: not added
moderate
AE: Abdominal pain, diarrhea, transient ↑LFTs; Rare: neutropenia with prolonged use

Mefloquine

Brand: Lariam / generic mefloquine
Class: Antimalarial
Subclass: Quinoline-methanol
PK: t½ 20 days | Clearance: hepatic
Max Dose: 1500 week
severe
AE: Neuropsychiatric reactions (anxiety, depression, nightmares, psychosis), dizziness, nausea, vomiting, bradycardia, rare seizures.

Megestrol Acetate

Brand: Megace (US/EU) / Megetrol (IN) / Megace (BD)
Class: Endocrine
Subclass: Progestin (appetite stimulant)
PK: t½ 20 hours | Clearance: hepatic
Max Dose: 800 day
severe
AE: Thromboembolism, adrenal suppression, edema, hyperglycemia

Meloxicam

Brand: Mobic (global) / Melocam, Meloxic (IN/BD)
Class: NSAID
Subclass: Oxicam derivative (preferential COX-2 inhibitor)
PK: t½ 20 hours | Clearance: hepatic
Max Dose: 15 day
moderate
AE: Dyspepsia, nausea, edema, increased BP, renal impairment; rare SJS/TEN

Memantine

Brand: Namenda (US/EU) / Ebixa (EU) / Memantine (IN/BD)
Class: Neurological
Subclass: NMDA receptor antagonist (uncompetitive)
PK: t½ 70 hours | Clearance: renal
Max Dose: 20 day
moderate
AE: Dizziness, headache, confusion, constipation, hypertension, somnolence

Mesalazine

Brand: Asacol (US/EU) / Pentasa (US/EU) / Mesacol (IN) / Salofalk (BD)
Class: Gastrointestinal
Subclass: 5-Aminosalicylic acid (anti-inflammatory)
PK: t½ 1 hours | Clearance: renal
Max Dose: 4800 day
moderate
AE: Headache, nausea, abdominal pain, diarrhea; rare nephrotoxicity, myocarditis

Metformin

Brand: Glucophage / Glycomet (IN) / Diabetmin (BD)
Class: Antidiabetic
Subclass: Biguanide
PK: t½ 6 hours | Clearance: renal
Max Dose: 2550 day
moderate
AE: Gastrointestinal upset (nausea, diarrhea, metallic taste), B12 deficiency with long-term use, RARE: lactic acidosis (risk in renal/hepatic/cardiac failure)

Methotrexate

Brand: Trexall (global) / Methotrexate (IN/BD generic)
Class: Anticancer
Subclass: Antimetabolite (antifolate)
PK: t½ 8 hours | Clearance: renal
Max Dose: not added
severe
AE: Myelosuppression, hepatotoxicity, mucositis, nephrotoxicity at high dose

Methyldopa

Brand: Aldomet (US/EU) / Dopamet (IN) / Methyldop (BD)
Class: Antihypertensive
Subclass: Centrally acting α₂-adrenergic agonist (Prodrug)
PK: t½ 2 hours | Clearance: renal
Max Dose: 2000 day
moderate
AE: Sedation, dry mouth, fatigue, hemolytic anemia, hepatic dysfunction

Metoprolol

Brand: Lopressor (US/EU) / Metocard (IN) / Betaloc (IN) / Metoprolol (BD)
Class: Antihypertensive
Subclass: Beta-1 selective blocker
PK: t½ 3.5 hours | Clearance: hepatic
Max Dose: 400 day
moderate
AE: Bradycardia, hypotension, dizziness, fatigue

Metronidazole

Brand: Flagyl (US/EU) / Metrogyl (IN) / Metrix (BD)
Class: Antibiotic
Subclass: Nitroimidazole (anaerobes, protozoa)
PK: t½ 8 hours | Clearance: hepatic
Max Dose: 1500 day
moderate
AE: Metallic taste, GI upset, neuropathy (prolonged), disulfiram-like reaction with alcohol

Midazolam

Brand: Versed (US/EU) / Mezolam (IN) / Midatin (BD)
Class: Sedative/Hypnotic
Subclass: Benzodiazepine sedative (GABA-A positive allosteric modulator)
PK: t½ 3 hours | Clearance: hepatic
Max Dose: 10 day
severe
AE: Severe respiratory depression, hypotension, apnea, amnesia

Midodrine

Brand: ProAmatine / Gutron
Class: Sympathomimetic
Subclass: Alpha-1 selective agonist
PK: t½ 0.5 hours | Clearance: renal
Max Dose: 30 day
moderate
AE: Supine hypertension, piloerection, pruritus, urinary retention

Minoxidil

Brand: Loniten (US/EU) / Mintop (IN) / Regain (BD)
Class: Antihypertensive
Subclass: Direct vasodilator (Potassium channel opener)
PK: t½ 4 hours | Clearance: hepatic
Max Dose: 40 day
severe
AE: Edema, tachycardia, hypertrichosis, pericardial effusion

Mirtazapine

Brand: Remeron (US/EU) / Mirtaz (IN) / Remer (BD)
Class: Antidepressant
Subclass: NaSSA (Noradrenergic and specific serotonergic antidepressant)
PK: t½ 30 hours | Clearance: hepatic
Max Dose: 45 day
moderate
AE: Weight gain, increased appetite, sedation, dry mouth

Moxifloxacin

Brand: Avelox (US/EU) / Moxicip (IN) / Moxet (BD)
Class: Antibiotic
Subclass: Fluoroquinolone (respiratory)
PK: t½ 12 hours | Clearance: hepatic
Max Dose: 400 day
severe
AE: QT prolongation, tendonitis, CNS effects, dysglycemia

Moxonidine

Brand: Physiotens (EU) / Moxcent (IN) / Moxon (BD)
Class: Antihypertensive
Subclass: Imidazoline receptor agonist (centrally acting)
PK: t½ 2.5 hours | Clearance: renal
Max Dose: 0.6 day
mild
AE: Dry mouth, headache, dizziness, fatigue, bradycardia